Why the study?
Does electroporation occur during clinically relevant defibrillation shocks and affect therapy outcomes?
Population
Heart tissue
Design
Review
Key result
Electroporation of heart tissue occurs during clinically relevant defibrillation shocks and can affect therapy outcomes by being both pro- and anti-arrhythmic.
Authors
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Should not alter defibrillation protocols; leaves open whether electroporation modulation could refine future therapies.
Does electroporation occur during clinically relevant defibrillation shocks and affect therapy outcomes?
This review highlights that electroporation occurs during standard defibrillation and can influence therapy outcomes by being both pro- and anti-arrhythmic.
Nikolski et al. (2005) conducted a review in Life-threatening arrhythmias. Defibrillation shocks was evaluated. Electroporation of heart tissue occurs during clinically relevant defibrillation shocks and can affect therapy outcomes by being both pro- and anti-arrhythmic.