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March 21, 2018West Indian Medical Journal3 citationsOpen Access

Anthropometry and Blood Pressure Changes in a Caribbean Adolescent Population of African Ancestry. An Evaluation of Longitudinal Data Using a Multilevel Mixed Regression Approach

SNSelby NicholsFCF Cadogan

Key Result

Systolic blood pressure increased by 1.27 and 3.09 mmHg per year among females and males, respectively, with weight, BMI, and percentage body fat being the strongest determinants of blood pressure change.

Study Design

Type

Cohort

Multicenter

No

Structured PICO

P
Population
Adolescents of African ancestry entering secondary school in Tobago, followed annually over a five-year period to evaluate anthropometric determinants of blood pressure changes.
C
Comparator
Cross-sectional data from adolescents of similar age group from the same population
O
Outcome
Annual rate of change in systolic and diastolic blood pressuresurrogate

Anthropometric measures, particularly weight and BMI, are strong determinants of age-related blood pressure changes in adolescents of African ancestry, and cross-sectional data provide a valid proxy for longitudinal estimates.

Limitations

  • No adjustments to the estimates were made for level of maturation and physical activity, both of which are known to influence blood pressure levels.
  • No adjustments to the estimates were made for level of maturation and physical activity

Abstract

OBJECTIVE: The aim of this study was to determine the effect of growth pattern on blood pressure changes in an adolescent population of African ancestry based on longitudinal data and to compare this with estimates derived from cross-sectional data. METHODS: Participants had measurements of weight, height, blood pressure and percentage body fat taken annually using standardized procedures. Annual blood pressure and anthropometry velocities as well as one- and three-year interval gender specific tracking coefficients were computed. We investigated whether changes in blood pressure could be explained by measures of growth using a multilevel mixed regression approach. RESULTS: The results showed that systolic blood pressure (SBP) increased by 1.27 and 3.09 mmHg per year among females and males, respectively. Similarly, diastolic blood pressure (DBP) increased by 1.16 and 1.92 mmHg per year among females and males, respectively. Multilevel analyses suggested that weight, body mass index, percentage body fat and height were the strongest anthropometric determinants of blood pressure change in this population. The results also suggest that there are gender differences in the relative importance of these anthropometric measures with height playing a minor role in predicting blood pressure changes among adolescent females. With the exception of DBP at 18 years among females, there were no significant differences between mean blood pressure generated from cross-sectional and longitudinal data by age in both males and females. CONCLUSION: Anthropometric measures are important covariates of age-related blood pressure changes and cross-sectional data may provide a more cost-effective and useful proxy for generating age-related blood pressure estimates in this population.

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Cite This Study

Nichols et al. (2018) conducted a cohort in Blood pressure changes. Anthropometric changes (weight, height, BMI, percentage body fat) was evaluated on Annual change in systolic and diastolic blood pressure. Systolic blood pressure increased by 1.27 and 3.09 mmHg per year among females and males, respectively, with weight, BMI, and percentage body fat being the strongest determinants of blood pressure change.

synapsesocial.com/papers/6a1ec3c349c1593eca9a8547https://doi.org/10.7727/wimj.2012.002
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