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Abstract In 1964 the first population based cohort was examined at the Glostrup Hospital and ever sinvce follow-ups and baseline studies of new cohorts have been going on. The main focus of the first and most following studies was coronary heart disease risk factor epidemiology. The participants in each cohort have been drawn as random samples from the background population in up to 11 municipalities in the Copenhagen region. An overall design has been built which covers both cross sectional, longitudinal and time-sequential designs. Of the 38 633 invited to one of the 15 baseline examinations 23 647 have participated. At all baseline investigations comprehensive clinical and biochemical data as well as data from questionnaires and interviews have been collected.
Osler et al. (2010) studied this question.