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May 1, 2004Journal of Clinical Investigation333 citations

Anemia of inflammation: the cytokine-hepcidin link

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NANancy C. Andrews

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Abstract

The anemia of inflammation, commonly observed in patients with chronic infections, malignancy, trauma, and inflammatory disorders, is a well-known clinical entity. Until recently, we understood little about its pathogenesis. It now appears that the inflammatory cytokine IL-6 induces production of hepcidin, an iron-regulatory hormone that may be responsible for most or all of the features of this disorder.

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Nancy C. Andrews (2004) studied this question.

synapsesocial.com/papers/6a712b1de71d69abee0914fdhttps://doi.org/10.1172/jci21441
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