In AF patients fully eligible for long-term anticoagulation, should left atrial appendage closure be offered as a first-line alternative to NOACs given a noninferior composite but a higher ischemic stroke signal?

Active since Jun 2020

Heat

Patients affected

Experts on record

0/1

Resolution

No fixed date yet

Sources

How this gets settled

Resolving trial — not yet identified

Resolution

No fixed date yet

What settles itResolving-trial readout

The debate

Offer the device earlyvsKeep pills first-line

Who could settle it

0 of 1 on record

DNDevi Nair, MD

0 of 1 experts on record

Who this affects

Affected rangeEstimate

4.6M–7.6M

disputed HR 1.46 (not significant)target HR < 1.38

Get involved

Preview

DNGMJHPOMS

Not yet tracked

WatchSteer thisSoon

Sources & verification

26linked & dated sources

VerifiedConfirmed against a primary source (registry API or dual-model citation gate).EstimateA computed estimate (e.g. comparable-based cost or modeled range), not a measured value.Scan-reportedReported by the scan and linked to its source — not yet independently verified.