Supplementary Figure S4 from First-in-Human Phase I/IIa Study of the First-in-Class CDK2/4/6 Inhibitor PF-06873600 Alone or with Endocrine Therapy in Patients with Breast Cancer
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MAIN FINDING: The study evaluates a new CDK2/4/6 inhibitor's effect on tumor reduction in breast cancer patients.
KEY EVIDENCE: Results showed changes in tumor size measured by the percent change from baseline, assessed using RECIST v1.1 criteria.
APPROACH: The trial involved a full analysis set and examined both the inhibitor alone and in combination with endocrine therapy.
SIGNIFICANCE: Findings could inform future treatments for breast cancer, highlighting a potential new option for therapy.
Resumen
Supplementary Figure S4. Waterfall plot for best percent change from baseline in sum of diameters for target lesions based on investigator assessment (RECIST v1.1) - full analysis set, Part 2.
Supplementary Figure S4 from First-in-Human Phase I/IIa Study of the First-in-Class CDK2/4/6 Inhibitor PF-06873600 Alone or with Endocrine Therapy in Patients with Breast Cancer | Synapse