Supplementary Figure 4 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer | Synapse
July 15, 2025
Supplementary Figure 4 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer
Puntos clave
Main finding demonstrates that ISR pathway inhibition impacts multiple immune checkpoints in lung cancer.
Key evidence includes in vitro and in vivo data showing effects of ISR inhibition on cancer cell behavior.
Approach involved examining the integrated stress response in relation to immune checkpoints using various models.
Significance lies in its potential to inform new treatment strategies for lung cancer by targeting the ISR pathway.
Resumen
Supplementary Figure 4 shows the effect of ISR pathway inhibition in vitro and in vivo.
Me gusta
Guardar
Compartir
Me gusta
Guardar
Compartir
Cite This Study
Thomas-Jardin et al. (Tue,) studied this question.