ABSTRACT Background The pursuit of youthful skin reflects its association with health and well‐being. Energy‐based procedures are increasingly favored for their noninvasive nature and ability to target signs of aging at the tissue level through controlled thermal or mechanical stimulation. Aims This study evaluated the HIFES combined with synchronized radiofrequency (RF) as a noninvasive wrinkle treatment. Methods Thirty‐three patients underwent four treatments using HIFES and synchronized RF. Follow‐up visits occurred at 1 and 3 months post‐treatment. Wrinkle severity was assessed using 3D photographs and expressed as a percentage change, while 2D photographs were evaluated using the Global Aesthetic Improvement Scale (GAIS) and the Fitzpatrick Wrinkle and Elastosis Scale (FWES). Patient‐reported outcomes included a 5‐point Likert scale satisfaction survey and a comfort questionnaire. Results Significant wrinkle reduction was observed. 3D analysis showed wrinkle improvements of 20.13% ± 0.33% post‐treatment, 23.15% ± 0.32% at 1 month, and 35.36% ± 3.34% at 3 months. At 3 months, 88% of participants improved by at least one GAIS point. FWES score declined from 5.6 to 3.8, reflecting a shift from wrinkle severity class II to I. High satisfaction and comfort were reported. Conclusions HIFES combined with synchronized RF effectively reduces wrinkle severity, as evidenced by objective measurements and patient feedback. This noninvasive treatment offers a safe and well‐tolerated option for improving skin appearance and quality.
Robb et al. (Fri,) studied this question.