Oncology is benefiting from new semiconducting particles called quantum dots, which are nanocrystals with a size between 2 to 10 nm. Due to their sensitivity to quantum confinement effects they are capable of emitting monochromatic light thus enabling enhanced visualization of tissue architecture and early identification of cancers. Biocompatible and easily size and shape controlled, QDs can be surface-modified with biomolecules attached to specific receptors, enhancing the therapeutic effects of drugs. These applications include, among others, imaging, photodynamic therapy, biosensing; and real-time evaluation of treatment response and metastasis. New approaches are being proposed in the ways QD is synthesized and surface modified, hence opens up newer prospects in clinical diagnostics and drug delivery systems. In the course of clinical investigation, QDs are programmed to herald a new age in cancer detection and treatment, as far as sensitivity and efficacy are concerned. This paper reviews the preparation of QDs, their incorporation strategies and emerging roles of QDs in oncology this discrimination shall show how QDs have the ability to revolutionize molecular medicine and provide better solutions towards cancer treatment.
Hussain et al. (Tue,) studied this question.
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