Thrombosis in Brothers With Protein S Deficiency: Case Series

Puntos clave

• Thrombosis risk is significantly elevated in individuals with protein S deficiency, particularly affecting unusual sites.
• Key evidence suggests early diagnosis and long-term anticoagulation can significantly improve outcomes in affected families.
• Observational analysis of brothers with hereditary protein S deficiency reveals patterns of VTE and associated complications.
• Early familial screening for protein S deficiency may allow for preventative measures and reduced complications in relatives.