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September 10, 2025

Antibiotics, analgesics, and antifungals are commonly implicated in acute generalized exanthematous pustulosis; a retrospective analysis of 1410 cases

Puntos clave

AGEP commonly triggered by medications, with most cases linked to antibiotics and analgesics.
Analysis revealed 1410 AGEP cases from the FDA adverse events reporting database, highlighting medication risks.
Retrospective analysis utilized the FDA adverse events reporting database to identify implicated medications.
Findings suggest awareness of drug-induced AGEP is crucial for safe medication practices and monitoring.

Resumen

Acute generalized exanthematous pustulosis (AGEP) is a cutaneous adverse reaction commonly triggered by medications. In this study, we retrospectively analyzed cases of AGEP following monotherapy using the FDA Adverse events reporting database. We find that majority of the offending agents were antibiotics, analgesics, and antifungals while anticonvulsants, cardiovascular medications, and antimalarials were also implicated.

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Cite This Study

Pathak et al. (Wed,) studied this question.

synapsesocial.com/papers/68c187339b7b07f3a0611a10 https://doi.org/https://doi.org/10.1093/ced/llaf402

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