Supplementary Figure 5 from Microbiota Shape Metabolic and Immune Determinants of CAR-T Therapy and Correlate with Outcomes in Myeloma

Puntos clave

• Antibiotic use significantly modifies gut microbiota composition in multiple myeloma patients, affecting treatment outcomes.
• Comparison of patients receiving antibiotics and those who did not reveals distinct shifts in microbiota at critical points in treatment.
• Assessment utilized principal component analysis (PCA) to effectively illustrate differences in intestinal microbiota profiles.
• Findings suggest gut microbiota could be pivotal in determining the effectiveness of CAR-T therapies.