What type of study is this?

This is a In Vitro Study study.

September 10, 2025Open Access

19F NMR-Tags for Peptidyl Prolyl Conformation Analysis

GHGeorge S. M. Hanson FBFaidra BatsakiUniversity of Edinburgh TMTeagan L MyerscoughUniversity of Edinburgh

Puntos clave

Proline cis/trans isomerism affects protein folding dynamics and interactions.
Cis/trans isomerism analysis revealed slow exchange rates significant for protein behavior.
NMR techniques were applied to study peptidyl prolyl conformation with high precision.
Understanding these interactions can enhance insights into protein functionalities.

Resumen

Proline cis/trans isomerism plays an important role in protein folding and mediating protein-protein interactions in Short Linear Interacting Motifs within intrinsically disordered protein regions. The slow exchange rate between cis...

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Cite This Study

Hanson et al. (Wed,) studied this question.

synapsesocial.com/papers/68c189e79b7b07f3a0613e6e https://doi.org/https://doi.org/10.1039/d5cb00118h

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