Abstract: Rheumatoid arthritis is a chronic autoimmune disease with joint destruction and chronic inflammation symptoms. Conventional therapy focuses on the prevention of the progression of the disease and management of symptoms, rather than curing the disease. Emerging therapies have been developed to cure the disease, which combines conventional therapies with a novel drug delivery system. Novel therapies have better bioavailability, which is marked by reduced adverse reactions. In the following article, some of the emerging therapies focused on the notable advancement in the procurement of the RA include microRNA alteration, helper T-cell inhibition, drug repurposing, targeting sites for interleukins, and blocking of signaling pathways. Beyond pharmacological intervention, emerging therapies explore the modulation of the microbiome, epigenetic regulation, and the manipulation of immune tolerance mechanisms. These therapies offer hope for better disease control and potential advantages for future betterment.
Romi et al. (Tue,) studied this question.