What type of study is this?

This is a Genomic analysis study (also classified as: Whole Genome Sequencing, Phylogenetic Analysis).

September 10, 2025Open Access

Genomic analysis of Neisseria meningitidis serogroup W causing invasive meningococcal disease in four travellers from Saudi Arabia, Italy, 2025

Puntos clave

Genomic analysis revealed four cases of invasive meningococcal disease caused by neisseria meningitidis serogroup W.
The isolates were whole genome sequenced, identifying them as sequence type 11 within clonal complex 11.
Phylogenetic analysis positioned the genomes within the Hajj strain sublineage, indicating a potential epidemiological link.
The isolates showed susceptibility to ceftriaxone, ciprofloxacin, penicillin G, and rifampicin, suggesting treatment options.

Resumen

Genomic analysis was performed on Neisseria meningitidis isolates from four cases of invasive meningococcal disease (IMD) identified in Italy after travel to Saudi Arabia in 2025. The cases were not epidemiologically related. The isolates from the cases were whole genome sequenced and belonged to serogroup W, sequence type (ST)-11, clonal complex (CC)11 and were susceptible to ceftriaxone, ciprofloxacin, penicillin G and rifampicin. Phylogenetic analysis grouped the four genomes with the Hajj strain sublineage.

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Cite This Study

Neri et al. (Thu,) studied this question.

synapsesocial.com/papers/68c1bd2a54b1d3bfb60edf4c https://doi.org/https://doi.org/10.2807/1560-7917.es.2025.30.31.2500483

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