Intraductal papilloma (IP) is a benign tumor, which is very rare in male breast. In this report, we report a 50-year-old Chinese man who presented with a painless mass in his right breast accompanied by occasional small amount of bloody discharge. Mammography and MRI showed a subareolar nodule graded as the Breast Imaging-Reporting and Data System category 4. The patient underwent mammary gland excision through an incision along the lower edge of areola. Histopathologic examination demonstrated multiple intraductal papilloma with atypical ductal hyperplasia (ADH). There are nine cases of IP with ADH have been reported in PubMed (English language) literature until now. The most common presenting symptom is duct blood discharge. It is difficult to distinguish benign and malignant papillary lesions from invasive cancer by radiologically, should have a histopathological evaluation.
Zheng Sun (Fri,) studied this question.