What type of study is this?

This is a Quantitative Study study.

September 17, 2025

Free-Breathing Lung MR Fingerprinting at 0.55T with Retrospective Respiratory Motion Binning

Puntos clave

Free-breathing lung MR Fingerprinting successfully measured T1 and T2 in healthy subjects, showing feasibility for clinical use.
Average T1 values were 645±123ms during inspiration and 638±129ms during expiration, while T2 values were 42±2ms and 44±2ms respectively.
Data was collected using a 30-second free-breathing MRF sequence at 0.55T with respiratory self-navigation for improved accuracy.
Highlights the potential for monitoring pulmonary diseases, such as emphysema and COPD, through advanced imaging techniques.

Resumen

Motivation: Quantitative mapping may enable early detection/monitoring of pulmonary diseases, with free-breathing imaging essential for patients with compromised lung capacity. Goal(s): This work aims to develop free-breathing 2D lung MR Fingerprinting T1, T2, and M0 mapping at 0.55T with respiratory self-navigation. Approach: Data were acquired in three healthy subjects using a 30-second free-breathing MRF sequence at 0.55T with respiratory self-navigation Respiratory motion-resolved maps were obtained using a Deep Image Prior reconstruction. Results: Free-breathing 0.55T lung MRF was successful in all subjects, yielding average values of 645±123ms (inspiration) and 638±129ms (expiration) for T1, and 42±2ms (inspiration), and 44±2ms (expiration) for T2. Impact: This work demonstrates feasibility of free-breathing lung MR Fingerprinting for respiratory motion-resolved 2D T1, T2 and M0 mapping at 0.55T in healthy subjects, which may have potential clinical applications to pulmonary conditions, such as emphysema, COPD, and interstitial lung diseases.

Me gusta

Guardar