What type of study is this?

This is a Quantitative Study study.

September 17, 2025

Free-running Fast-Interrupted Steady-State 5D whole-heart MRI of congenital heart disease patients without the use of contrast agents

Puntos clave

5D FISS CMR provides comparable images to 2D and 3D methods in congenital heart disease evaluation within six minutes.
Contrast and sharpness measurements show that 5D FISS MRI can effectively replace standard imaging techniques.
The approach involves analyzing contrast metrics from 2D and 3D CMR versus 5D FISS to demonstrate feasibility.
This method may simplify heart assessments for CHD patients by eliminating the need for contrast agents.

Resumen

Motivation: Easy-to-use and time-efficient whole-heart imaging that can be performed, without the need for contrast agents, remains an unmet need in the evaluation of congenital heart disease patients. Goal(s): To demonstrate the feasibility of native contrast 5D FISS CMR and compare it to established 2D and 3D methods in CHD patients. Approach: Contrast and sharpness measurements from 2D and 3D CMR are quantitatively compared to those from 5D FISS. Results: 5D FISS CMR with native contrast in a fixed six-minute scan time provides comparable images to standard 2D and 3D CMR building towards a simplified method for evaluating CHD without contrast agents. Impact: Free-running Fast-Interrupted Steady-State 5D whole-heart MRI enables the evaluation of the cardiac anatomy in patients with congenital heart disease within a fixed six-minute scan time and without contrast agents.

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