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September 23, 2025Open Access

Paget's bone disease, clinical case report

Puntos clave

The case demonstrates notable improvement after bisphosphonate treatment in a 34-year-old female with paget's disease.
Initial symptoms included significant knee pain and bone deformity, found in both radiographs and scintigraphy.
Treatment involved bisphosphonates, leading to noticeable improvement in symptoms within 3 months.
Paget's disease often affects older males, highlighting the rarity of this case in a younger female patient.

Resumen

Paget's disease is a disorder affecting bone metabolism due to accelerated bone remodeling. It mainly affects the pelvis, spine, lower extremity bones, and skull. It is believed to be the result of a combination of genetic and environmental factors; its incidence has decreased in recent years. Symptoms are usually absent; however, some report bone pain. Treatment aimed to prevent bone remodeling by using bisphosphonates. We present the case of a 34-year-old female with pain and bone deformity of the knee of 5 months of evolution, in radiographs and scintigraphy, with signs compatible with Paget's disease. Bisphosphonates were administered, and there was improvement after 3 months. This is a relevant case because the incidence of Paget's disease is higher in men over 40 years of age.

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Cite This Study

A Mon, study studied this question.

synapsesocial.com/papers/68d4759931b076d99fa6d816 https://doi.org/https://doi.org/10.37135/ee.04.24.07