Dental caries poses a widespread oral health challenge demanding effective treatments that patients find agreeable. Our research zeroes in on crafting and assessing eugenol-infused herbal chewable tablets to combat tooth decay. Eugenol, a substance drawn from clove oil, boasts pain-relieving, germ-fighting, and swelling-reducing qualities - a perfect fit for dental use. We fashioned these herbal chew tablets via direct compression throwing in suitable additives to nail down key tablet traits like toughness, crumbliness, and how fast they break down. Due to excellent to good flow property and compression ability of powder blend, direct compression method was used for the formulation of chewable tablets. They checked weight changes, thickness, hardness, crumbliness, and drug spread and found satisfactory results. Lab tests revealed how fast eugenol released from the tablets. The team also studied how well these eugenol-packed tablets fought common mouth germs that rot teeth, like Streptococcus mutans and concluded that it has good antibacterial effect. With the help of findings, formulation 8 (F-8) was determined as optimized batch among all the batches. The results showed the chewable tablets had good physical and chemical qualities. Eugenol left the tablets at a proper rate. Antibacterial tests proved the tablets packed a punch against bacteria that cause tooth decay. People find it easier to take chewable tablets kids and older folks.
Bade et al. (Fri,) studied this question.