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AbstractBackground: Observational studies show high pre-diagnosis 25-hydroxyvitamin D is associated with lower mortality after colorectal cancer (CRC) diagnosis. Results from clinical trials suggest vitamin D supplementation may improve outcomes among CRC patients. Most studies included few Black Americans, who typically have lower 25-hydroxyvitamin D. We evaluated associations between serum 25-hydroxyvitamin D and mortality after CRC diagnosis among Black American cases. Methods: Data arose from 218 Black Americans from the Southern Community Cohort Study diagnosed with CRC during follow-up (age 40-79 at enrollment). Pre-diagnostic 25-hydroxyvitamin D was measured at enrollment and categorized as deficient (
Lawler et al. (Mon,) studied this question.