Review of Nanoemulgel for Treatment of Fungal Infections

The skin is the largest of the body’s organs and it has a big role to play in maintaining homeostasis and defending against microbial invaders. Fungal infections are responsible for a large proportion of the global burden of skin diseases; affecting millions, especially in developing countries. The application of antifungal drugs as topical agents is one of the best techniques to treat major fungal infections that affect the skin, which involves several advantages such as localized delivery, and lower systemic toxicity among others. These findings also suggest that nano-emulgel could be used as an alternative system for delivering drugs through topical administration. However, issues such as the inability to load bulky drug molecules and safety concerns about surfactants and gelling agents limit their potential use as drug carriers by this pathway. It is necessary to carefully study these issues further so that we can exploit fully what this nano-emulgel may offer in terms of dermatological medications.