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Mendelian randomization of plasma lipidome, inflammatory proteome and heart failure | Synapse

August 15, 2024Open Access

Mendelian randomization of plasma lipidome, inflammatory proteome and heart failure

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Resumen

Heart failure (HF) is a global health issue, with lipid metabolism and inflammation critically implicated in its progression. This study harnesses cutting-edge, expanded genetic information for lipid and inflammatory protein profiles, employing Mendelian randomization (MR) to uncover genetic risk factors for HF.

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Cite This Study

Zheng et al. (Thu,) studied this question.

synapsesocial.com/papers/68e5c0efb6db643587558946 https://doi.org/https://doi.org/10.1002/ehf2.14997

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Proteome-wide mendelian randomization investigates potential associations in heart failure and its etiology: emphasis on PCSK92024 · 8 citations
2Association of genetically predicted lipid traits and lipid-modifying targets with heart failure2022 · 30 citations
3Inflammation and heart failure: a two-sample Mendelian randomization study2022 · 28 citations
4Triglyceride-glucose index and the risk of heart failure: Evidence from two large cohorts and a mendelian randomization analysis2022 · 178 citations
5Inflammatory Cytokines and Chemokines as Therapeutic Targets in Heart Failure2020 · 410 citations