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October 8, 2025
Open Access
Table 2 from A First-In-Human Dose-Escalation Phase I Study of Basroparib, a Tankyrase Inhibitor, in Patients with Advanced-Stage Solid Tumors
CL
Christopher H. Lieu
University of Colorado Cancer Center
Heinz‐Josef Lenz
University of Pisa
Al B. Benson
Northwestern University
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Puntos clave
Adverse events related to basroparib were summarized, indicating outcomes of treatment.
Patients with advanced-stage solid tumors showed varying responses during dose-escalation.
The phase I study evaluated the safety and tolerability of basroparib.
Considering the advanced-stage tumors, findings support ongoing research into tankyrase inhibitors.
Resumen
Summary of AEs related to basroparib.
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Lieu et al. (Mon,) studied this question.
synapsesocial.com/papers/68e5c1ba6950a706b22b5383
https://doi.org/https://doi.org/10.1158/2767-9764.30284995
Table 2 from A First-In-Human Dose-Escalation Phase I Study of Basroparib, a Tankyrase Inhibitor, in Patients with Advanced-Stage Solid Tumors | Synapse