Monitoring of T2 changes in skeletal muscles using multiple overlapping-echo detachment imaging

Quantitative magnetic resonance imaging (qMRI), a noninvasive imaging tool without ionizing radiation, provides quantitative physiological information, whilst its lengthy scan time hinders its application in dynamic or real-time scenarios. Herein, the MOLED, a single-shot qMRI method we proposed previously, was applied in an ischemia and post-occlusive reactive hyperemia experiment to measure the T2 variation of the musculoskeletal system. The results disclose regular T2 fluctuations of different muscles during different periods. Inter-day repeatability experiments demonstrate that our method is accuracy and reliable.