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31P MRS could be valuable for the assessment of treatment response in pancreatic cancer. Using a 31P whole-body transmit coil in combination with a 16-channel receive array at 7T, we could obtain 31P MRSI data covering both the whole liver and the deeply lying pancreas. The aim of this study was to compare 31P metabolite levels in the pancreas and liver in healthy volunteers. The PME/PDE ratio, which has been used as a tumor marker, was 2.1-fold higher in the pancreas compared to the liver. This will be important to take into account when applying 31P MRS in pancreatic tumors.
Seelen et al. (Wed,) studied this question.