Can combined High-resolution and 3D-Arterial spin labeling MR differentiate moyamoya disease from arteriosclerotic moyamoya syndrome?

This study aimed to investigate whether the combined T1w-CUBE imaging and multiple post-labeling delay 3D pseudo-continuous arterial spin labeling imaging(MP 3D-PcASL)can distinguish moyamoya disease(MMD)from arteriosclerotic moyamoya syndrome(AS-MMS). 26 MMD patients and 25 AS-MMS patients were measured with T1w-CUBE imaging and MP 3D-PcASL. Significantly altered vessel wall in morphology and cerebral perfusion patterns were found on the lesions between AS-MMS and MMD. We thus concluded that the combined T1w-CUBE imaging and MP 3D-PcASL might help distinguish MMD from AS-MMS in clinic.