Zero-DeepSub: Zero-Shot Deep Subspace Reconstruction for Multiparametric Quantitative MRI Using QALAS

The 3D-quantification using an interleaved Look-Locker acquisition sequence with T2 preparation pulse (3D-QALAS) has been developed and used for acquiring high-resolution T1, T2, and PD maps from five measurements within each repetition time. However, it assumes that each k-space data is acquired instantly at the first echo train length index neglecting T1 and T2 relaxation during the acquisition, which might cause blurring and biases in the reconstructed maps. In this study, we propose to reconstruct accurate quantitative T1 and T2 maps with reduced blurring compared to the conventional QALAS method using our proposed zero-shot deep subspace reconstruction method (i.e., Zero-DeepSub).