Influence of fat deposition in T1 measurement of the liver: The value of T1 mapping with water component only using the 2D DIXON Look-Locker method

The purpose of this study was to elucidate the clinical importance of T1 mapping of the liver with the water component only using the 2D DIXON Look-Locker sequence. T1 values of the liver were compared among T1 maps obtained by IP, OP and DIXON Look-Locker sequences. T1 values of the liver on the T1 maps obtained from IP- and OP-based sequences were significantly influenced by an increased fat component. In contrast, the T1 value of the liver on the T1 maps with the water component only calculated from DIXON water images was unlikely to be influenced by hepatic steatosis.