A preliminary study of rapid T1mapping imaging for evaluating renal interstitial fibrosis

T1 mapping is a quantitative magnetic resonance imaging (MRI) technique that can reflect the extent of tissue fibrosis. Classical inversion recovery (IR) method can measure the T1 value with high accuracy, but it has long acquisition times. Therefore, the variable flip angle(VFA) method and the modified look‑locker inversion recovery method (MOLLI) are more frequently used in practical clinical applications. The objectives of this study was to compare the two rapid T1mapping imaging methods and to evaluate the diagnostic efficacy of T1 values measured by the two methods in differentiating the degree of renal interstitial fibrosis(IF).