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The quantification of decay rate R2* and susceptibility is useful in assessment of various neurological disorders manifesting iron accumulation and myelin loss. Conventional 3D GRE acquisition is sensitive to motion and B0 fluctuation due to its long scan time. In this study, we demonstrated improved reliability of multi-shot multi-echo 3D EPI when compared to GRE, showing reduced scan time and similar accuracy.
Huang et al. (Wed,) studied this question.
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