Novel water-fat separation model for multi-echo bipolar readout

This work proposes a new model for solving the water-fat separation problem with bipolar acquisition, which allows us for reducing the acquisition time and computing accurate PDFF without any special concerns about phase corrections. We solve jointly two water-fat separation problems for even and odd echoes, under the assumption that the concentrations are different, but considering the same field map and R₂^*. Bland Altman plots and linear regression show excellent performance for PDFF estimation in 8 healthy volunteers.