Identifying pathological differentiation of cervical squamous cell carcinoma with APTw and IVIM

The pathological differentiation of cervical squamous cell carcinoma (CSCC) determines the therapy method and prognosis. APTw, DWI and IVIM sequences were performed for predicting pathological differentiation. 27 patients with well-moderately differentiation, 13 patients with poorly differentiation and 15 healthy volunteers were enrolled. APT SI, ADC, D*, D and f values were calculated for comparing among different groups. Results showed parameters except D* differed significantly between CSCC and normal. There were statistically significant differences in AUC of APT SI, D and f between well-moderately group and poorly differentiated group. APTw and IVIM can be used to identify pathological differentiation of CSCC.