Brain glymphatic impairment correlates with motor dysfunction after ischemic stroke

This present study used diffusion tensor image analysis along the perivascular space (DTI-ALPS) method to investigate the glymphatic activity of the corticospinal tract in subacute ischemic stroke patients with impaired motor function. We found that the subacute ischemic stroke group had a lower DTI-ALPS value on the affected side of corticospinal tract, suggesting impairment of the glymphatic system in patients with subacute ischemic stroke, which may be related to motor dysfunction.