C3-Alkylation of Imidazo1,2-apyridines via Three-Component Aza-Friedel–Crafts Reaction Catalyzed by Y(OTf)3

As an important class of nitrogen-containing fused heterocyclic compounds, imidazo1,2-apyridines often exhibit significant biological activities, such as analgesic, anticancer, antiosteoporosis, anxiolytic, etc. Using Y(OTf)