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Demographic and clinical characteristics of patients with lung cancer. We collected two plasma cfDNA cohorts and two tumor tissue cohorts from patients with lung cancer. One sample was collected per patient. The plasma cfDNA samples were profiled using cfMethyl-Seq; the solid tumor samples were profiled using RRBS. The donors in plasma cfDNA cohorts are independent of those in the tissue cohort for marker discovery
Li et al. (Tue,) studied this question.