Vancomycin-resistant enterococci: A rising challenge to global health

IntroductionImproper antibiotic use triggers outbreaks of hospital-acquired VRE infections. Relevant studies were gathered from Scopus, and PubMed. Over two decades, prevalence of VRE in humans and animals grew from 0. 05% to 99. 0% globally and from 1. 0% to 45. 6% in India. Identifying VRE at the species level helps identify acquired/intrinsic resistance. Results and conclusionVRE infections, especially bloodstream infections, inflict significant mortality (60-70%-global; 23%-India) and economic burden (539 million). Linezolid and daptomycin are frequently used without adequate clinical trial evidence. India lacks studies on prevalence, mortality and cost, which needs political will, public-private partnership, and prioritizing public health.