FIGURE 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation

Analysis of SCFA concentrations in relation to chemotherapy response. Top: Mean SCFA concentrations in plasma and stool of patients with bladder cancer categorized by NAC response status (CR vs. NR), showing no significant differences. Bottom: Correlation matrices between SCFA levels and bacterial genera in plasma and stool, with the strongest positive and negative correlations marked, indicating the metabolic interactions within the GM in the context of cancer therapy response.