Role of Small Biopsy in Diagnosis of Spectrum of Endometrial Lesions: A Study From a Tertiary Care Centre in Greater Noida

Introduction: Histopathological characterization of endometrial biopsies and curettings constitute an important tool for diagnosis of endometrial pathology; whether benign, pre-malignant and malignant, and help the gynecologist to decide appropriate therapeutic strategy. The present study was carried out to document the histopathological appearances seen in endometrial biopsies, and their age–wise distribution in patients with infertility and abnormal uterine bleeding due to endometrial causes. A Materials and Methods: total of 75 specimens of endometrial curettings and biopsies from patients with abnormal uterine bleeding due to endometrial causes and inability to conceive, received in the Pathology department, Noida International Institute of Medical Science over a period of one year, were retrieved and analyzed retrospectively, and their ndings were documented. The tissue had been received in 10% formalin, processed routinely, and the slides had been stained with Hematoxylin and Eosin. : The most common histopathological diagnosis was disor Results dered proliferative endometrium, seen in 34.67% cases followed by proliferative endometrium in 14.67%, secretory phase endometrium (9.33%) and atropic endometrium( 8%). 9.33% biopsies showed pill endometrium. Retained products of conception were conrmed histologically in 4% cases. Endometrial hyperplasias were seen in 10.67% cases The most common nding in patients of infertility was proliferative endometrium indicating anovulatory cycles. Endometrial biopsy is a valuable tool in assessment of endometrial st Conclusion: atus in infertility, as well as benign and malignant pathology in abnormal uterine bleeding due to relative ease and accessibility of procedure and rapid availability of results.