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May 31, 2024

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Oral Sebetralstat for On-Demand Treatment of Hereditary Angioedema Attacks

MRMarc A. RiedlLa Jolla Institute for Immunology HFHenriette FarkasSemmelweis University EAEmel Aygören‐PürsünBeiersdorf (Germany)

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Resumen

Approved on-demand treatments for hereditary angioedema attacks need to be administered parenterally, a route of administration that is associated with delays in treatment or withholding of therapy.

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Cite This Study

Riedl et al. (Fri,) studied this question.

synapsesocial.com/papers/68e67617b6db6435875fffa1 https://doi.org/https://doi.org/10.1056/nejmoa2314192

Oral Sebetralstat for On-Demand Treatment of Hereditary Angioedema Attacks | Synapse

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Efficacy and Safety of Donidalorsen for Hereditary Angioedema2024 · 67 citations
2Ecallantide for the Treatment of Acute Attacks in Hereditary Angioedema2010 · 309 citations
3Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial2023 · 114 citations
4The Icatibant Outcome Survey: experience of hereditary angioedema management from six European countries2017 · 29 citations
5Treatment of HAE Attacks in the Icatibant Outcome Survey: An Analysis of Icatibant Self-Administration versus Administration by Health Care Professionals2015 · 47 citations