Supplementary Figure S2 from The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations

Supplementary Figure S2. A. Cell viability assays were conducted to assess IC50 measurements in FGFR3S249C UM-UC-14 parental cells (left) and wild-type, mock-transfected cells (right) when treated with specific FGFR inhibitors. B-C. Cell viability curves for FGFR3S249C UM-UC-14 cells carrying N540K (B) or V555M (C) kinase domain mutations and their response to KIN-3248 and other designated FGFR inhibitors.