Histopathological Spectrum of Lesions in Nephrectomy Specimens: A One Year Experience in Tertiary Care Hospital

Introduction - Kidneys are one of the major organs of the human body that serve several essential functions.Objectives -This study aimed to investigate and understand the various morphological patterns exhibited by renal diseases,as well as to assess their distribution across different age groups and genders.Materials and Methods -The present study was conducted at Department of Pathology, Department of pathology, Government Medical College, Surat. A total of 24 nephrectomy specimens were studied.Results -The study shows, male to female ratio is 1:1.4 with female preponderance and among 24 nephrectomy specimens 15 were non-neoplastic and 9 were neoplastic.Non- Neoplastic lesions constitute about 15 cases with hydronephrosis (4 cases) being the most common cause leading to nephrectomy. Among 9 Neoplastic cases most common cause being renal cell carcinoma (6 cases).In the age group between 5th to 6th decades, maximum number of non-neoplastic lesions and neoplastic lesions were seen and least was observed in between 1st to 2nd decade. Discussion -In the present study the most common findings of nephrectomy was hydronephosis and renal cell carcinoma.A rare case of lymphoproliferative disorder- B cell lymphoma with plasmacytic differentiantion also seen.Conclusion -These findings provide valuable insights into the histopathological patterns and the incidence of neoplastic and non-neoplastic lesions of kidney requiring nephrectomy in this institution.