HIV in pediatrics - Early diagnosis and infectious management

Introduction: Human immunodeficiency virus (HIV) infection in pediatrics represents a significant challenge for global health, as children can acquire the virus vertically during pregnancy, childbirth or breastfeeding. Children's vulnerability to HIV is accentuated by the risks associated with the mother-child bond. This study is based on a literature review, highlighting research that addresses the challenges and treatment strategies of the disease. Objective: The main objective of this study is to examine the approach to HIV in children, exploring research that discusses therapeutic strategies, early diagnosis and multidisciplinary approaches. Methods: A literature review was conducted in the MEDLINE database, using the PubMed search platform. English descriptors were used to cover global studies in the final search, excluding results prior to the last three years. Results and Discussion: Epidemiological data, diagnostic methods, pediatric antiretroviral treatments and psychosocial aspects related to HIV in children were analyzed. The studies analyzed reveal the importance of early diagnosis, through serological and polymerase chain reaction (PCR) tests, and the prompt initiation of antiretroviral therapy (ART). Furthermore, the need for multidisciplinary approaches to address ART-related disorders and the psychosocial complexities associated with childhood HIV infection was identified. Conclusion: The findings of the present study highlight the importance of early diagnosis, as well as the existence of challenges regarding the diagnosis itself and the infectious management of the disease. Mother-to-child transmission prevention programs must be expanded, and a combined effort that includes strategies to prevent maternal disease, early identification of infected women, and expansion of prophylactic and drug measures can lead to significant reductions in mother-to-child transmissions, as well as improved treatment. safe for HIV-infected babies and children.