Gene therapy for hereditary retinal diseases

This scientific literature review demonstrates high prospects of recent developments in gene therapy for the treatment of retinal diseases. First of all it concerns inherited pathologies such as retinitis pigmentosa and Leber congenital amaurosis. Nevertheless gene therapy is still quite far from its tangible application in clinical practice for other retinal diseases, although preliminary trial outcomes of its use for some of them (for example, achromatopsia, congenital X-linked retinoschisis) turn to be very promising. The data presented in this review inspire hope that gene therapy will be more accessible and widely-used in clinical practice. Key words:retinal diseases, inherited retinal diseases, gene therapy, voretigene neparvovec