Assessing the feasibility of time in tight range (TITR) targets with advanced hybrid closed loop (AHCL) use in children and adolescents: A single‐centre real‐world study

Abstract Aims Time in Tight Range (TITR) is a novel glycaemic metric in monitoring type 1 diabetes (T1D) management. The aim of this study was to assess the attainability of the TITR target in children and adolescents using the advanced hybrid closed loop (AHCL). Methods The 2128‐day CGM data from 56 children and adolescents with T1D using AHCL (Minimed‐780G) were analysed. Time in Range (TIR) (3.9–10 mmol/L), TITR (3.9–7.7 mmol/L), and other glycaemic parameters were separately analysed in terms of whole day, daytime (06.00–23:59), and nighttime (00.00–05.59) results. The participants were divided into two groups by autocorrection rate where Group 1 had a rate of 50% and >60% were 87% and 52%, respectively. When those with TITR >60% ( n : 29) and those without ( n : 27) were evaluated in terms of hypoglycaemia, no statistically significant difference was found in time below range (TBR) 3–3.9 mmol/L (0.3% vs. 2.1%, p : 0.084) and TBR 60% target. A target of >50% for TITR seems realistic in children with T1D using AHCL.