April 24, 2024Open Access

Hydroxychloroquine inhibits hemolysis-induced arterial thrombosis ex vivo and improves lung perfusion in hemin-treated mice

JBJoshua H. BourneAustralian Regenerative Medicine Institute GPGina PerrellaUniversity College Birmingham JEJuma El-AwaisiUniversity of Birmingham

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Resumen

Free labile hemin acts as a damage-associated molecular pattern during acute and chronic hemolysis and muscle injury, supporting platelet activation and thrombosis.

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Bourne et al. (Wed,) studied this question.

synapsesocial.com/papers/68e6dd4fb6db643587658b53 https://doi.org/https://doi.org/10.1016/j.jtha.2024.04.008

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