0248 The Role of Neighborhood Deprivation in Sleep Health

Abstract Introduction Previous studies, mostly with small sample sizes, demonstrate inconsistent associations between the socioeconomic neighborhood environment and sleep among adults. Using data from a large cohort, we examined the association between neighborhood deprivation and sleep health. Methods The Cancer Prevention Study-3 is a large prospective cohort of American men and women enrolled at baseline between 2006 and 2013. The Neighborhood Deprivation Index (NDI) was derived for US census tracts using principal components analysis of 2008-2012 American Community Survey data on poverty, income, occupation, housing, employment, and education. Participant addresses at baseline were geocoded to the tract level and linked to the NDI. Participants (N=180,592) self-reported, in categories, their sleep duration in a 24-hour period on weekdays and weekends on the 2015 follow-up questionnaire and sleep quality in 2018. Weekly habitual sleep duration was calculated from a weighted average of weekday and weekend durations. Multivariable logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for the association between NDI in quintiles and each sleep outcome, overall and by race and ethnicity. Results Participants had an average age of 48.6 (standard deviation=9.6) years and were predominantly women (79.2%). Most participants identified as White (93.5%), while smaller proportions identified with racial and ethnic minoritized populations (e.g., Black: 2.6%, Hispanic: 5.6%). Compared to the least deprived neighborhoods, living in the most deprived neighborhoods was associated with a 25% (OR=1.25, 95% CI 1.18-1.33) higher odds of short ( 7 hours) versus recommended (7-8 hours) sleep duration. Neighborhood deprivation was also associated with an increased odds of long sleep duration (≥9 hours; OR=1.13, 95% CI 1.06-1.21) and poor sleep quality (OR=1.06, 95% CI 1.01-1.10). Race and ethnicity modified the relationship between neighborhood deprivation and long sleep duration, such that the association was only observed among White participants. Conclusion Results from this large well-powered study indicate neighborhood deprivation may adversely impact sleep health by increasing the odds of shorter and longer than recommended sleep duration and poor sleep quality. More research in large diverse samples is needed to confirm these findings. Support (if any) Support: Support was provided by the National Institutes of Health (R01CA259192).