Mp01-14 Retroperitoneal Nodal Distribution of Metastatic Seminoma: A Clinical Mapping Study

You have accessJournal of UrologyPenile however, 1 of these 4 was detected on preoperative CT. Thus, based on preoperative imaging 3 (11%) of the 27 left sided primaries had microscopic disease outside the unilateral template. For right sided primary tumor, the interaortocaval (89.5%) is the most common landing zone, followed by para-caval (26.3%) and para-aortic (18.4%) regions. Seven (18.4%) patients had cross over to the para-aortic zone; however, 5 of these 7 was detected on preoperative CT. Thus, based on preoperative imaging, 2 (5%) of the 38 right sided primaries had microscopic disease outside of a unilateral template. Overall, the sensitivity, specificity, PPV and NPV of CT zonal detection are 78.9%, 99.5%, 97.3%, and 95.7%, respectively. CONCLUSIONS: The spread of seminoma in the retroperitoneum follows a similar but subtly different pattern compared to non-seminomatous germ cell tumors. Crossover occurs in 14.8-18.6% of patients. With negative CT imaging, the incidence of microscopic disease in the contralateral zone ranges from 5-11%. While CT is highly specific, it may miss up to 21.1% of anatomical zones. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e7 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Jiping Zeng More articles by this author Jacob McFadden More articles by this author Timothy A. Masterson More articles by this author Clint Cary More articles by this author Expand All Advertisement PDF downloadLoading ...