Acute Iliofemoral Deep Venous Thrombosis in Adolescents and Young Adults Is Unprovoked, Associated with Hypercoagulable States, and Has a High Incidence of Post-Thrombotic Syndrome

Acute iliofemoral deep vein thrombosis (IFDVT) in young adults and adolescents is a cause of lower extremity pain and edema that may lead to chronic debilitating symptoms. Treatment options include pharmaco/mechanical thrombectomy, stent placement, and anticoagulation. The lack of long-term data in young patients after venous stenting leads to variability in treatment with reluctance to employ stents in this population. The purpose of this study is to review the etiology, the incidence of post-thrombotic syndrome (PTS), and the role of intervention in young patients after IFDVT.