Pd04-12 Ic/BPS Chronicles: Exploring Childhood Urologic Histories in Adult Women With Interstitial Cystitis/Bladder Pain Syndrome

You have accessJournal of UrologyPediatrics I (PD04)1 May 2024PD04-12 IC/BPS CHRONICLES: EXPLORING CHILDHOOD UROLOGIC HISTORIES IN ADULT WOMEN WITH INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME Leah Beland, Jonathan Kaye, Lane Palmer, and Robert Moldwin Leah BelandLeah Beland , Jonathan KayeJonathan Kaye , Lane PalmerLane Palmer , and Robert MoldwinRobert Moldwin View All Author Informationhttps://doi.org/10.1097/01.JU.0001008812.05762.7f.12AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a growing problem among adult women. Its risk factors and pathophysiology remain largely unknown. To our knowledge, little data exists on the childhood urologic history of adult IC/BPS patients. We sought to identify if adult women with IC/BPS had any history of urology disorders or symptoms during childhood that may have predisposed them to develop IC/BPS as adults. METHODS: A total of 141 women were diagnosed with IC/BPS at a tertiary care center with expertise in pelvic pain and underwent cystourethroscopy to exclude other pathology. An additional 150 adult females without urological symptoms were included as controls. All subjects completed a questionnaire pertaining to childhood urologic history and associated adult urologic conditions, if applicable. RESULTS: Mean age of IC/BPS subjects was 52.5 years vs 48.9 years (p=NS) for controls. In total, 51/141 IC/BPS subjects (36.2%) and 2/150 controls (1.3%) had a history of significant pediatric lower tract pathology (p<0.001). Specifically, 31 IC/BPS (22.0%) patients reported childhood symptoms of urgency, frequency, enuresis, and encopresis versus 1 control (0.7%) (p<0.001). Twenty (14.2%) IC/BPS subjects experienced childhood UTIs compared to only 1 (0.7%) of the controls (p<0.001). Among IC/BPS subjects with a history of childhood urologic disorders, the mean duration of adult symptoms was 9.1 years, indicating a latency period between the resolution of childhood symptoms and onset of adult symptoms. CONCLUSIONS: The striking difference in prevalence of pediatric urologic disorders among women with IC/BPS compared to healthy controls may implicate childhood urologic disorders as a risk factor for the development of IC/BPS in adulthood. Long-term prospective studies of childhood lower tract disorders are needed to define the risks that may affect girls who develop IC/BPS as adults. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e88 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Leah Beland More articles by this author Jonathan Kaye More articles by this author Lane Palmer More articles by this author Robert Moldwin More articles by this author Expand All Advertisement PDF downloadLoading ...